Unemployment Rate in New Madrid County, MO was 7.10% in February of 2024, according to the United States Federal Reserve. Historically, Unemployment Rate in New Madrid County, MO reached a record high of 18.00 in February of 1990 and a record low of 2.30 in September of 2022. Trading Economics provides the current actual value, an historical data chart and related indicators for Unemployment Rate in New Madrid County, MO - last updated from the United States Federal Reserve on May of 2024.